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oven baked pork tenderloin sliced on a cutting board.
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5 from 1 vote

Oven Pork Tenderloin

A super easy recipe to make pork tenderloin in the oven so it's flavorful. It's perfect for weeknights!
Prep Time10 minutes
Cook Time25 minutes
Cooling Time10 minutes
Total Time45 minutes
Course: Dinner Recipes
Cuisine: American
Servings: 4 servings
Calories: 421kcal
Author: Samantha Erb

Ingredients

  • 2.5 pound pork tenderloin
  • 1/4 cup Cajun seasoning e.g., Slap Ya Mama
  • 2 tablespoons olive oil

Instructions

  • Preheat your oven to 375 degrees F (190 degrees C)
  • Sprinkle Cajun seasoning evenly on the outside of the pork tenderloin, covering all sides.
  • (Optional, but recommended) Heat olive oil in a skillet over medium-high heat. Add the seasoned pork tenderloin and brown it on all sides, turning occasionally. This should take about 5 minutes.
  • Once the pork is browned, place it in the preheated oven.
  • Roast the pork in the hot oven until the thickest part of the meat reaches an internal temperature of 145 degrees F (63 degrees C), about 20-25 minutes. Use an instant-read thermometer to check for doneness.
  • Once cooked, take out the pork tenderloin from the oven and let it rest for about 10 minutes. This allows the juices to be redistributed.
  • After resting, slice the juicy pork tenderloin into 1-inch thick pieces using a sharp knife. Serve the sliced pork tenderloin with your choice of sides, such as green beans, mashed potatoes with gravy, or sweet potatoes.

Nutrition

Calories: 421kcal | Carbohydrates: 4g | Protein: 59g | Fat: 18g | Saturated Fat: 4g | Polyunsaturated Fat: 3g | Monounsaturated Fat: 9g | Trans Fat: 0.1g | Cholesterol: 184mg | Sodium: 152mg | Potassium: 1268mg | Fiber: 2g | Sugar: 1g | Vitamin A: 3330IU | Vitamin C: 0.1mg | Calcium: 33mg | Iron: 4mg